FB2025_01 , released February 20, 2025
Gene: Dmel\Cht2
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General Information
Symbol
Dmel\Cht2
Species
D. melanogaster
Name
Chitinase 2
Annotation Symbol
CG2054
Feature Type
FlyBase ID
FBgn0022702
Gene Model Status
Stock Availability
Gene Summary
Enables chitinase activity. Involved in several processes, including chitin catabolic process; chitin-based cuticle development; and ecdysis, chitin-based cuticle. Located in external side of apical plasma membrane and extracellular space. Is expressed in several structures, including adult head; embryonic head epidermis; epidermis; gut section; and sensory nervous system primordium. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic). (Alliance, FBgn0022702 )
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Also Known As

DmCht2

Key Links
Genomic Location
Cytogenetic map
Sequence location
Recombination map
3-1.0
RefSeq locus
NT_037436 REGION:1752328..1755934
Sequence
Genomic Maps
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The following external sites may use different assemblies or annotations than FlyBase.
Function

GO Summary Ribbons

enzyme
regulator
receptor
receptor binding
transporter
structural molecule
cytoskeletal binding
DNA binding
RNA binding
transcription factor
small molecule binding
metal ion binding
lipid binding
carbohydrate binding
other molecular_function
molecular function
cell cycle/proliferation
cell organization/biogenesis
transport/localization
development
reproduction
immune system
nervous system process
behavior
response to stimulus
signaling
gene expression
protein metabolism
DNA metabolism
small molecule metabolism
other biological_process
biological process
extracellular region
cytosol
cytoskeleton
mitochondrion
nucleus
chromosome
membrane
cell periphery
cell junction
cell projection
endomembrane system
synapse
macromolecular complex
other cellular_component
cellular component
Gene Ontology (GO) Annotations (14 terms)
Molecular Function (3 terms)
Biological Process (8 terms)
Cellular Component (3 terms)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. (Q9W092)
Summaries
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Expression Data

Gene ToolKit

Alleles, Insertions, Transgenic Constructs, and Aberrations
Variants
Phenotypes
Orthologs
Paralogs
Human Disease Associations
Functional Complementation Data
Interactions
Pathways
Class of Gene
Genomic Location and Detailed Mapping Data
Stocks and Reagents
Other Comments
Relationship to Other Genes
Nomenclature History
Synonyms and Secondary IDs (9)
Datasets (0)
External Crossreferences and Linkouts ( 51 )
References (61)