FB2025_01 , released February 20, 2025
Gene: Dmel\αCOP
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General Information
Symbol
Dmel\αCOP
Species
D. melanogaster
Name
Coat Protein (coatomer) α
Annotation Symbol
CG7961
Feature Type
FlyBase ID
FBgn0025725
Gene Model Status
Stock Availability
Gene Summary
Predicted to enable structural molecule activity. Involved in male meiosis cytokinesis; protein localization to cleavage furrow; and regulation of lipid storage. Located in endoplasmic reticulum-Golgi intermediate compartment. Part of COPI vesicle coat. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; epithelium; gut section; and male germline cell. Human ortholog(s) of this gene implicated in autoimmune interstitial lung, joint, and kidney disease. Orthologous to human COPA (COPI coat complex subunit alpha). (Alliance, FBgn0025725 )
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Also Known As

α-COP

Key Links
Genomic Location
Cytogenetic map
Sequence location
Recombination map
3-0.5
RefSeq locus
NT_037436 REGION:1641066..1645199
Sequence
Genomic Maps
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Function

GO Summary Ribbons

enzyme
regulator
receptor
receptor binding
transporter
structural molecule
cytoskeletal binding
DNA binding
RNA binding
transcription factor
small molecule binding
metal ion binding
lipid binding
carbohydrate binding
other molecular_function
molecular function
cell cycle/proliferation
cell organization/biogenesis
transport/localization
development
reproduction
immune system
nervous system process
behavior
response to stimulus
signaling
gene expression
protein metabolism
DNA metabolism
small molecule metabolism
other biological_process
biological process
extracellular region
cytosol
cytoskeleton
mitochondrion
nucleus
chromosome
membrane
cell periphery
cell junction
cell projection
endomembrane system
synapse
macromolecular complex
other cellular_component
cellular component
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (1 term)
Biological Process (8 terms)
Cellular Component (2 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
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Summaries
Gene Model and Products
Expression Data

Gene ToolKit

Alleles, Insertions, Transgenic Constructs, and Aberrations
Variants
Phenotypes
Orthologs
Paralogs
Human Disease Associations
Functional Complementation Data
Interactions
Pathways
Class of Gene
Genomic Location and Detailed Mapping Data
Stocks and Reagents
Other Comments
Relationship to Other Genes
Nomenclature History
Synonyms and Secondary IDs (11)
Datasets (0)
External Crossreferences and Linkouts ( 52 )
References (87)