Located in endomembrane system. Is expressed in adult head; adult heart; and organism. Orthologous to human RRBP1 (ribosome binding protein 1).
The gene aluminum tubes is referred to in FlyBase by the symbol Dmel\alt (CG18212, FBgn0038535). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (2 unique). Gene sequence location is 3R:17673732..17682515. Its molecular function is unknown. The biological processes in which it is involved are not known. 19 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; partially lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages.
Please see the JBrowse view of Dmel\alt for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\alt using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
JBrowse - Visual display of RNA-Seq signals
View Dmel\alt in JBrowseThe gene 'ToolKit' contains a set of key genetic reagents that can be used to study a gene. A single reagent for each category is chosen based on frequency of usage, and stock availability. Click "See all" to view all the reagents for the category.
Category | Common alleles (# stocks) |
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Classical and Insertion Alleles | |
Loss of function allele | |
Amorphic allele | |
Fluorescently-tagged allele | |
Transgenic Constructs | |
UAS RNAi | |
UAS wild-type cDNA | |
Untagged genomic rescue | |
Fluorescently-tagged genomic rescue | |
Aberrations | |
Deficiency | |
Duplication |
3-61
3-60.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
CG31251- CG31360+ CG31249- Overall orientation not stated: CG14322+ CG7523- ald+ CG18212- CG7655+
"CG18212" is not involved in anything of any importance to female meiosis, but two deceitful interlopers (two Doc element insertions isolated in a mutant screen) attempted to mislead the authors into thinking that it was critically important, thus they decided to name the gene "alt", which stands for "aluminum tubes", because when someone presents you with pictures of aluminum tubes and tells you that they are intended for nuclear uses, you must be very careful about the inferences you make.